Abstract: There are many people in China who suffered from physical and mental diseases and need physical and psychological rehabilitation. Traditional treatments can work in rehabilitation, but will take much money and labor. In recent years, virtual reality (VR) technology has become a new direction to innovate rehabilitation. This paper summarizes the research results of VR technology in rehabilitation for stroke, anxiety, depression and autism. Based on these results, we propose a framework for VR rehabilitation system with virtual agents. A prototype system is developed to corroborate the proposed design guidelines. With the prototype rehabilitation system, autistic children can train their life skills in different scenarios. Preliminary test results show the proposed framework can push users to take the rehabilitation training actively and can be a new method for rehabilitation training.

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